The production of reactive oxygen species by complex I.
作者： Judy Hirst , Martin S. King , Kenneth R. Pryde
DOI: 10.1042/BST0360976
关键词: Flavin mononucleotide 、 Electron transport chain 、 Biology 、 Submitochondrial particle 、 Oxidative stress 、 Reverse electron flow 、 Superoxide 、 Biochemistry 、 Oxidoreductase 、 Reactive oxygen species
摘要: … and differences between them and progress towards combining … The free radical theory of aging proposes that it is a major … In a detailed study using rat brain mitochondria, Starkov and …
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biochemsoctrans.org参考文章(40)
A Boveris, E Cadenas, A O M Stoppani, Role of ubiquinone in the mitochondrial generation of hydrogen peroxide Biochemical Journal. ,vol. 156, pp. 435- 444 ,(1976) , 10.1042/BJ1560435
Tatyana V. Votyakova, Ian J. Reynolds, ΔΨm‐Dependent and ‐independent production of reactive oxygen species by rat brain mitochondria Journal of Neurochemistry. ,vol. 79, pp. 266- 277 ,(2008) , 10.1046/J.1471-4159.2001.00548.X
Anatoly A. Starkov, Gary Fiskum, Regulation of brain mitochondrial H2O2 production by membrane potential and NAD(P)H redox state Journal of Neurochemistry. ,vol. 86, pp. 1101- 1107 ,(2003) , 10.1046/J.1471-4159.2003.01908.X
Holly R. McLennan, Mauro Degli Esposti, The contribution of mitochondrial respiratory complexes to the production of reactive oxygen species. Journal of Bioenergetics and Biomembranes. ,vol. 32, pp. 153- 162 ,(2000) , 10.1023/A:1005507913372
Alberto Boveris, Britton Chance, The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen. Biochemical Journal. ,vol. 134, pp. 707- 716 ,(1973) , 10.1042/BJ1340707
Todd B. Sherer, Ranjita Betarbet, Claudia M. Testa, Byoung Boo Seo, Jason R. Richardson, Jin Ho Kim, Gary W. Miller, Takao Yagi, Akemi Matsuno-Yagi, J. Timothy Greenamyre, Mechanism of toxicity in rotenone models of Parkinson's disease. The Journal of Neuroscience. ,vol. 23, pp. 10756- 10764 ,(2003) , 10.1523/JNEUROSCI.23-34-10756.2003
Leonid A Sazanov, Philip Hinchliffe, Structure of the Hydrophilic Domain of Respiratory Complex I from Thermus thermophilus Science. ,vol. 311, pp. 1430- 1436 ,(2006) , 10.1126/SCIENCE.1123809
Adrian J. Lambert, Martin D. Brand, Inhibitors of the quinone-binding site allow rapid superoxide production from mitochondrial NADH:ubiquinone oxidoreductase (complex I). Journal of Biological Chemistry. ,vol. 279, pp. 39414- 39420 ,(2004) , 10.1074/JBC.M406576200
Sandeep Raha, Brian H Robinson, Mitochondria, oxygen free radicals, disease and ageing Trends in Biochemical Sciences. ,vol. 25, pp. 502- 508 ,(2000) , 10.1016/S0968-0004(00)01674-1
Takahiro Yano, Sergey Magnitsky, Tomoko Ohnishi, Characterization of the complex I-associated ubisemiquinone species: toward the understanding of their functional roles in the electron/proton transfer reaction. Biochimica et Biophysica Acta. ,vol. 1459, pp. 299- 304 ,(2000) , 10.1016/S0005-2728(00)00164-X