Cell cycle-related kinase mediates viral-host signalling to promote hepatitis B virus-associated hepatocarcinogenesis
作者： Zhuo Yu , Yue-Qiu Gao , Hai Feng , Ying-Ying Lee , May S Li
DOI: 10.1136/GUTJNL-2013-305584
关键词: HBx 、 Cell cycle 、 Chromatin immunoprecipitation 、 Transcriptional regulation 、 Molecular biology 、 RNA interference 、 Cancer research 、 Regulation of gene expression 、 Kinase 、 Biology 、 Gene silencing 、 Gastroenterology
摘要: Background Androgen receptor (AR) signalling contributes to male predominance in hepatocellular carcinoma (HCC), which is more pronounced in HBV-endemic areas. Cell …
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researchgate.net 参考文章(34)
YE TIAN, HAN WAN, GUANG TAN, Cell cycle-related kinase in carcinogenesis. Oncology Letters. ,vol. 4, pp. 601- 606 ,(2012) , 10.3892/OL.2012.828
Mark A Feitelson, Helena MGPV Reis, Jie Liu, Zhaorui Lian, Jingbo Pan, Hepatitis B virus X antigen (HBxAg) and cell cycle control in chronic infection and hepatocarcinogenesis. Frontiers in Bioscience. ,vol. 10, pp. 1558- 1572 ,(2005) , 10.2741/1640
Alfa HC Bai, Alfred SL Cheng, Alliance of epigenetic forces for the activation of oncogenic Wnt/β-catenin signaling. Journal of Gastroenterology and Hepatology. ,vol. 28, pp. 383- 385 ,(2013) , 10.1111/JGH.12090
Augusto Villanueva, Josep M. Llovet, Targeted Therapies for Hepatocellular Carcinoma Gastroenterology. ,vol. 140, pp. 1410- 1426 ,(2011) , 10.1053/J.GASTRO.2011.03.006
Henry Chan, Joseph Sung, Hepatocellular carcinoma and hepatitis B virus. Seminars in Liver Disease. ,vol. 26, pp. 153- 161 ,(2006) , 10.1055/S-2006-939753
Wan-Jen Yang, Ching-Ju Chang, Shiou-Hwei Yeh, Wei-Hsiang Lin, Sheng-Han Wang, Ting-Fen Tsai, Ding-Shinn Chen, Pei-Jer Chen, Hepatitis B virus X protein enhances the transcriptional activity of the androgen receptor through c-Src and glycogen synthase kinase-3β kinase pathways† Hepatology. ,vol. 49, pp. 1515- 1524 ,(2009) , 10.1002/HEP.22833
Alexandra Klaus, Walter Birchmeier, Wnt signalling and its impact on development and cancer Nature Reviews Cancer. ,vol. 8, pp. 387- 398 ,(2008) , 10.1038/NRC2389
Sheng-Han Wang, Shiou-Hwei Yeh, Wei-Hsiang Lin, Hurng-Yi Wang, Ding-Shinn Chen, Pei-Jer Chen, Identification of androgen response elements in the enhancer I of hepatitis B virus: a mechanism for sex disparity in chronic hepatitis B. Hepatology. ,vol. 50, pp. 1392- 1402 ,(2009) , 10.1002/HEP.23163
Hashem B. El-Serag, Epidemiology of Viral Hepatitis and Hepatocellular Carcinoma Gastroenterology. ,vol. 142, pp. 1264- 1273.e1 ,(2012) , 10.1053/J.GASTRO.2011.12.061
Dae-Yeul Yu, Hyung-Bae Moon, Jin-Kyong Son, Sangkyun Jeong, Seong-Lan Yu, Heesik Yoon, Yong-Mahn Han, Chul-Sang Lee, Jung-Sun Park, Chul-Ho Lee, Byung-Hwa Hyun, Seishi Murakami, Kyung-Kwang Lee, Incidence of hepatocellular carcinoma in transgenic mice expressing the hepatitis B virus X-protein Journal of Hepatology. ,vol. 31, pp. 123- 132 ,(1999) , 10.1016/S0168-8278(99)80172-X