Benzylated and prenylated flavonoids from the root barks of Cudrania tricuspidata with pancreatic lipase inhibitory activity.
作者： Yang Hee Jo , Seon Beom Kim , Qing Liu , Jin Woo Lee , Bang Yeon Hwang
DOI: 10.1016/J.BMCL.2015.07.017
关键词: Stereochemistry 、 Pancreatic lipase 、 Moraceae 、 Cudrania tricuspidata 、 Chemistry 、 Prenylation 、 Absolute configuration
摘要: Abstract A new benzylated and prenylated flavonone, cudracuspiflavanone ( 17 ) were isolated from the roots of Cudrania tricuspidata (Moraceae), together with two chromones 1 – 2 fourteen flavonoids 3 16 ). The structures compounds determined on basis spectroscopic analysis. absolute configuration was also defined by CD Among compounds, 14 15 inhibited pancreatic lipase activity an IC 50 value 9.0 6.5 μM, respectively.
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