Growth hormone gene regulation: a paradigm for cell-type-specific gene activation.
作者： Michael Karin , José-Luis Castrillo , Lars E. Theill
DOI: 10.1016/0168-9525(90)90100-K
关键词: Homeobox 、 Genetics 、 Cell type specific 、 Anterior pituitary 、 Biology 、 Cellular differentiation 、 Gene 、 Regulation of gene expression 、 Growth hormone
摘要: The growth hormone (GH) gene is specifically expressed within specialized cells of the anterior pituitary. central role in GH activation played by GHF-1, a homeodomain protein that itself
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