Isotopic and modeling investigation of long-term protein turnover in rat tissues

作者: Nathalie Poupin , Jean-François Huneau , François Mariotti , Daniel Tomé , Cécile Bos

DOI: 10.1152/AJPREGU.00310.2012

关键词: BiochemistryAmino acidIn vivoProtein turnoverKinetic fractionationSkeletal muscleLeucine kineticsChemistryIsotopes of nitrogenTRACER

摘要: Fractional synthesis rates (FSR) of tissue proteins (P) are usually measured using labeled amino acid (AA) tracer methods over short periods time under acute, particular conditions. By combining...

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