The Plasma Lipoproteins: Current Concepts of Metabolism and Structure with Clinical Implications

摘要: The work I will summarize on the plasma lipoproteins comes from many laboratories and has been recently reviewed in considerable detail (1–5). emphasize information which is pertinent to structure metabolism with clinical medicine, beginning definitions classifications. All of appear spherical negatively stained electron micrographs (Fig. 1). chylomicrons, carry dietary triglyceride, are largest particles elevated Type V hyperlipoproteinemia by Fredrickson, Levy Lees typing system. very low density (VLDL) second size. They triglyceride made endogenously body increased concentration types IIb, III, IV hyperlipoproteinemia. (LDL) one-half two-thirds cholesterol high IIa IIb. or alpha-lipoproteins do not enter classification but may be important atherosclerosis. There also a family called intermediate (IDL), have between VLDL IDL. Clinical interest recent years due largely known risk development premature