Ensuring the Safety and Security of Frozen Lung Cancer Tissue Collections through the Encapsulation of Dried DNA.

作者: Kevin Washetine , Mehdi Kara-Borni , Simon Heeke , Christelle Bonnetaud , Jean-Marc Félix

DOI: 10.3390/CANCERS10060195

关键词: Tumor tissueBiologyBiotechnologyFrozen tissueLung cancerSecurity systemBiobank

摘要: Collected specimens for research purposes may or not be made available depending on their scarcity and/or the project needs. Their protection against degradation in event of an incident is pivotal. Duplication and storage a different site best way to assure sustainability. The conservation samples at room temperature (RT) by duplication can facilitate protection. We describe security system collection non-small cell lung cancers (NSCLC) stored biobank Nice Hospital Center, France, lyophilized (dried), encapsulated DNA kept RT. Therefore, three frozen tissue collections from non-smoking, early stage sarcomatoid carcinoma NSCLC patients were selected this study. was extracted, RT under anoxic conditions using DNAshell technology. In total, 1974 987 encapsulated. Six two capsules each sample biobanks Grenoble (France) Hospitals, respectively. conclusion, maintained allows conservation, durability interest biobanks. This low-cost safe technology that requires limited amount space has low environmental impact.

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