Sustainable Synthesis of Flavonoid Derivatives, QSAR Study and Insecticidal Activity against the Fall Armyworm, Spodoptera frugiperda (Lep.: Noctuidae)

摘要: A simple, clean, solvent-free preparation of flavones by the use a silica-supported Preyssler heteropolyacid as reusable catalyst is described. High selectivity and very good yields (87-94%) were obtained in short reaction times (7-13 min). Bioassays for insecticidal activity against Spodoptera frugiperda carried out with set flavones. showed that some had moderate activity. Quantitative structure-activity relationships established on available data purpose predicting number structurally related relationship between molecular structure biological proposed.