Gut microbiota community adaption during young children fecal microbiota transplantation by 16s rDNA sequencing
作者： Jian-Lei Gu , Yi-Zhong Wang , Shi-Yi Liu , Guang-Jun Yu , Ting Zhang
DOI: 10.1016/J.NEUCOM.2016.01.095
关键词: Fecal microbiota 、 Pasteurellaceae 、 Physiology 、 16S ribosomal RNA 、 Transplantation 、 Gastrointestinal disease 、 Gut flora 、 Treatment method 、 Medicine 、 Fecal bacteriotherapy
摘要: Fecal microbiota transplantation (FMT) is to restore the intestinal environment of a diseased individual by using from healthy donor. In recent years, FMT has been developed into useful treatment method for various chronic gastrointestinal disease. There are already some works attempt explain mechanism this diseases in adult patients. However, much less effort focused on pediatric disorders. work, we have invited 3 young children with immune-mediated disorders treated surgery, and systematically investigated their temporal changes fecal after 16s rDNA sequencing technology. According our observations, composition these patients appears obviously interindividual variability significantly increased species richness The abundance Pasteurellaceae was remarkably during all three
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