Gut microbiome and the risk factors in central nervous system autoimmunity

摘要: Humans are colonized after birth by microbial organisms that form a heterogeneous community, collectively termed microbiota. The genomic pool of this macro-community is named microbiome. gut microbiota essential for the complete development immune system, representing binary network in which interact with host providing important and physiologic function conversely bacteria protect themselves from defense. Alterations balance microbiome due to combination environmental genetic factors can now be associated detrimental or protective effects experimental autoimmune diseases. These alterations unbalance gastrointestinal responses influence distal effector sites leading CNS disease including both demyelination affective disorders. current range risk MS includes makeup elements. Of interest review consistency between We postulate serves as niche where different merge, thereby influencing process.