The Second Brain: Is the Gut Microbiota a Link Between Obesity and Central Nervous System Disorders?

摘要: The gut-brain axis is a bi-directional integrated system composed by immune, endocrine, and neuronal components which the gap between gut microbiota brain significantly impacted. An increasing number of different microbial species are now postulated to regulate function in health disease. westernized diet hypothesized be cause current obesity levels many countries, major socio-economical problem. Experimental epidemiological evidence suggest that responsible for significant immunologic, neuronal, endocrine changes lead obesity. We hypothesize microbiota, associated with diet, affect may possibly contribute development mental illness. In this review, we discuss links dysbiosis, obesity, immunologic neurologic diseases impact behavior.