Recent developments in the effects of nitric oxide-donating statins on cardiovascular disease through regulation of tetrahydrobiopterin and nitric oxide.

作者: Sze Ma , Christopher Cheng-Hwa Ma

DOI: 10.1016/J.VPH.2014.08.001

关键词: Vascular permeabilitySmooth muscle hyperplasiaNitric oxideTetrahydrobiopterinNADPH oxidaseSide effectPharmacologyMevalonate pathwayStatinMedicine

摘要: … guanosine triphosphate (GTP) to dihydroneopterin triphosphate, pyruvoyltetrahydrobiopterin and finally to BH4 [1], [2], [28]. The conversion of GTP to dihydroneopterin triphosphate by …

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