Recent advances in drug delivery strategies for treatment of ovarian cancer

摘要: Introduction: Ovarian cancer is associated with the highest mortality rate of all gynecological malignancies, due in part to inadequate treatment strategies and asymptomatic nature disease. Current standard care includes surgery systemic chemotherapy. However, this approach can result toxicities eventual disease relapse, emergence multidrug resistance. Drug delivery systems (DDS) have shown promise overcoming many limitations facing conventional regimens. Areas covered: This review provides an overview recent advances DDS for ovarian cancers. Nano-sized systems, including nanoparticles, micelles, liposomes drug conjugates; microspheres; implants injectable depots are discussed. The advantages, clinical potential these also outlined. Expert opinion: enable passive targeting tumors their size, further improvements tumor localization be made u...