Hypoxia — a key regulatory factor in tumour growth

作者: Adrian L. Harris

DOI: 10.1038/NRC704

关键词: Cell biologyApoptosisSignal transductionAngiogenesisCancer cellBiologyNeovascularizationVascular endothelial growth factor AHypoxia (medical)Tumor hypoxia

摘要: … Cancer cells have adapted these pathways, allowing tumours to survive and even grow … Hypoxic conditions reduce proliferation and increase apoptosis in wild-type embryonic stem cells…

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