作者: David Semela , Jean-François Dufour
关键词: Angiogenesis 、 Vascular endothelial growth factor C 、 S1PR1 、 Vascular endothelial growth factor 、 Vascular endothelial growth factor A 、 Vasculogenesis 、 Vascular endothelial growth factor B 、 Biology 、 Cancer research 、 Vascular endothelial growth inhibitor
摘要: Vascular endothelial growth factor (VEGF) is the main driving force for angiogenesis and vasculogenesis. Identified as a vascular cell mitogen survival factor, it has been sequenced cloned by Ferrara Connolly in 1989 [74, 84]. Intense research over past years deciphered gene, molecular pathways, receptors functions of this angiogenic [35]. VEGF thought to play an important role liver regeneration, hepatic fibrogenesis, portal hypertension, hepatocarcinogenesis malignant ascites formation.