Vascular Endothelial Growth Factor Signaling

作者: David Semela , Jean-François Dufour

DOI: 10.1007/3-540-27194-5_8

关键词: AngiogenesisVascular endothelial growth factor CS1PR1Vascular endothelial growth factorVascular endothelial growth factor AVasculogenesisVascular endothelial growth factor BBiologyCancer researchVascular endothelial growth inhibitor

摘要: Vascular endothelial growth factor (VEGF) is the main driving force for angiogenesis and vasculogenesis. Identified as a vascular cell mitogen survival factor, it has been sequenced cloned by Ferrara Connolly in 1989 [74, 84]. Intense research over past years deciphered gene, molecular pathways, receptors functions of this angiogenic [35]. VEGF thought to play an important role liver regeneration, hepatic fibrogenesis, portal hypertension, hepatocarcinogenesis malignant ascites formation.

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