Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes.
作者： Myoung Sook Kim , Ho Jeong Kwon , You Mie Lee , Jin Hyen Baek , Jae-Eun Jang
DOI: 10.1038/86507
关键词:
摘要: Low oxygen tension influences tumor progression by enhancing angiogenesis; and histone deacetylases (HDAC) are implicated in alteration of chromatin assembly and tumorigenesis. …
nature.com
elsevier.com
researchgate.net 
sci-hub.se 参考文章(45)
E R Maher, F M Richards, A R Webster, N A Affara, A H Prowse, F Resche, S Richard, S Olschwang, Somatic inactivation of the VHL gene in Von Hippel-Lindau disease tumors. American Journal of Human Genetics. ,vol. 60, pp. 765- 771 ,(1997)
R. Pili, A. Passaniti, G. R. Martin, D. S. Grant, R. M. Taylor, P. V. Long, Y. Guo, R. R. Pauly, J. A. Haney, A simple, quantitative method for assessing angiogenesis and antiangiogenic agents using reconstituted basement membrane, heparin, and fibroblast growth factor. Laboratory Investigation. ,vol. 67, pp. 519- 528 ,(1992)
Elizabeth E. Cameron, Kurtis E. Bachman, Sanna Myöhänen, James G. Herman, Stephen B. Baylin, Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer Nature Genetics. ,vol. 21, pp. 103- 107 ,(1999) , 10.1038/5047
Michael Grunstein, Histone acetylation in chromatin structure and transcription Nature. ,vol. 389, pp. 349- 352 ,(1997) , 10.1038/38664
Yuji Hinoda, Hiroyuki Yamamoto, Kohzoh Imai, Fumio Itoh, Inverse association of cell adhesion regulator messenger RNA expression with metastasis in human colorectal cancer Cancer Research. ,vol. 56, pp. 3605- 3609 ,(1996)
Peter Carmeliet, Yuval Dor, Jean-Marc Herbert, Dai Fukumura, Koen Brusselmans, Mieke Dewerchin, Michal Neeman, Françoise Bono, Rinat Abramovitch, Patrick Maxwell, Cameron J. Koch, Peter Ratcliffe, Lieve Moons, Rakesh K. Jain, Désiré Collen, Eli Keshet, Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature. ,vol. 394, pp. 485- 490 ,(1998) , 10.1038/28867
Leonidas Tsiokas, Vikas P. Sukhatme, Debabrata Mukhopadhyay, Wild-Type p53 and v-Src Exert Opposing Influences on Human Vascular Endothelial Growth Factor Gene Expression Cancer Research. ,vol. 55, pp. 6161- 6165 ,(1995)
Xinsheng Nan, Huck-Hui Ng, Colin A. Johnson, Carol D. Laherty, Bryan M. Turner, Robert N. Eisenman, Adrian Bird, Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex Nature. ,vol. 393, pp. 386- 389 ,(1998) , 10.1038/30764
Cornelius Schmaltz, Patricia Harrigan Hardenbergh, Audrey Wells, David E. Fisher, Regulation of Proliferation-Survival Decisions during Tumor Cell Hypoxia Molecular and Cellular Biology. ,vol. 18, pp. 2845- 2854 ,(1998) , 10.1128/MCB.18.5.2845
Mikhail V. Blagosklonny, Won G. An, Larisa Y. Romanova, Jane Trepel, Tito Fojo, Len Neckers, p53 Inhibits Hypoxia-inducible Factor-stimulated Transcription * Journal of Biological Chemistry. ,vol. 273, pp. 11995- 11998 ,(1998) , 10.1074/JBC.273.20.11995