Somatic inactivation of the VHL gene in Von Hippel-Lindau disease tumors.

作者: E R Maher , F M Richards , A R Webster , N A Affara , A H Prowse

DOI:

关键词: Cancer researchPoint mutationVon Hippel–Lindau diseaseMissense mutationPheochromocytomaLoss of heterozygosityCarcinogenesisAllelic heterogeneityGermline mutationBiology

摘要: Von Hippel-Lindau (VHL) disease is a dominantly inherited disorder predisposing to retinal and CNS hemangioblastomas, renal cell carcinoma (RCC), pheochromocytoma, and …

参考文章(0)