Crossroads of Signaling Pathways

作者: Stefania Staibano

DOI: 10.1007/978-94-007-7149-9_8

关键词:

摘要: As studies on PC progression continue to uncover a growing number of crosstalks and co-occurrences mutations epigenetic alterations, new drugs are getting approved bringing significant changes in the treatment paradigm these tumors.

参考文章(111)
Rosemary J Akhurst, Rik Derynck, TGF-β signaling in cancer – a double-edged sword Trends in Cell Biology. ,vol. 11, ,(2001) , 10.1016/S0962-8924(01)02130-4
KATSUYA NAKANO, YOSHITATSU FUKABORI, NOBUYUKI ITOH, WEIQIN LU, MIKIO KAN, WALLACE L. MCKEEHAN, HIDETOSHI YAMANAKA, Androgen-stimulated human prostate epithelial growth mediated by stromal-derived fibroblast growth factor-10. Endocrine Journal. ,vol. 46, pp. 405- 413 ,(1999) , 10.1507/ENDOCRJ.46.405
Rik Derynck, Ying E. Zhang, Smad-dependent and Smad-independent pathways in TGF-β family signalling Nature. ,vol. 425, pp. 577- 584 ,(2003) , 10.1038/NATURE02006
Heike Peterziel, Sigrun Mink, Annette Schonert, Matthias Becker, Helmut Klocker, Andrew CB Cato, Rapid signalling by androgen receptor in prostate cancer cells. Oncogene. ,vol. 18, pp. 6322- 6329 ,(1999) , 10.1038/SJ.ONC.1203032
P Pittoni, S Piconese, C Tripodo, M P Colombo, Tumor-intrinsic and -extrinsic roles of c-Kit: mast cells as the primary off-target of tyrosine kinase inhibitors. Oncogene. ,vol. 30, pp. 757- 769 ,(2011) , 10.1038/ONC.2010.494
Lorella Bonaccorsi, Sara Marchiani, Monica Muratori, Gianni Forti, Elisabetta Baldi, Gefitinib (‘IRESSA’, ZD1839) inhibits EGF-induced invasion in prostate cancer cells by suppressing PI3 K/AKT activation Journal of Cancer Research and Clinical Oncology. ,vol. 130, pp. 604- 614 ,(2004) , 10.1007/S00432-004-0581-8
Yong Wu, Weidong Zhao, Jingbo Zhao, Jiangping Pan, Qiaqia Wu, Yuanfei Zhang, William A. Bauman, Christopher P. Cardozo, Identification of androgen response elements in the insulin-like growth factor I upstream promoter. Endocrinology. ,vol. 148, pp. 2984- 2993 ,(2007) , 10.1210/EN.2006-1653
Jiri Zavadil, Erwin P Böttinger, TGF-beta and epithelial-to-mesenchymal transitions. Oncogene. ,vol. 24, pp. 5764- 5774 ,(2005) , 10.1038/SJ.ONC.1208927