Tumor-intrinsic and -extrinsic roles of c-Kit: mast cells as the primary off-target of tyrosine kinase inhibitors.
作者： P Pittoni , S Piconese , C Tripodo , M P Colombo
DOI: 10.1038/ONC.2010.494
关键词: Platelet-derived growth factor receptor 、 Tyrosine kinase 、 Receptor tyrosine kinase 、 Tumor progression 、 Stromal cell 、 Biology 、 Cancer research 、 Stem cell 、 Mast cell 、 Stem cell factor
摘要: … As a member of the PDGFR family, c-Kit receptor is characterized by an extracellular ligand-binding region containing five immunoglobulin-like repeats, a transmembrane sequence, an …
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