Measures of Autozygosity in Decline: Globalization, Urbanization, and Its Implications for Medical Genetics
作者： Michael A Nalls , Javier Simon-Sanchez , J Raphael Gibbs , Coro Paisan-Ruiz , Jose Tomas Bras
DOI: 10.1371/JOURNAL.PGEN.1000415
关键词: Linkage disequilibrium 、 Demography 、 Effective population size 、 Panmixia 、 Population 、 Biology 、 Inbreeding 、 Cohort 、 Genetics 、 Runs of Homozygosity 、 Consanguinity
摘要: … , urbanization, and population admixture. Using multiple measures of the genomic manifestations of distant consanguinity, we showed significant trends towards decreasing levels of …
paperity.org
elsevier.com
researchgate.net 参考文章(16)
Igor Rudan, Inbreeding and cancer incidence in human isolates. Human Biology. ,vol. 71, pp. 173- 187 ,(1999)
Joel N Hirschhorn, Genetic approaches to studying common diseases and complex traits. Pediatric Research. ,vol. 57, pp. 74- 77 ,(2005) , 10.1203/01.PDR.0000159574.98964.87
A. D. Carothers, I. Rudan, I. Kolcic, O. Polasek, C. Hayward, A. F. Wright, H. Campbell, P. Teague, N. D. Hastie, J. L. Weber, Estimating Human Inbreeding Coefficients: Comparison of Genealogical and Marker Heterozygosity Approaches Annals of Human Genetics. ,vol. 70, pp. 666- 676 ,(2006) , 10.1111/J.1469-1809.2006.00263.X
J. Raphael Gibbs, Andrew Singleton, Application of Genome-Wide Single Nucleotide Polymorphism Typing: Simple Association and Beyond PLOS Genetics. ,vol. 2, ,(2006) , 10.1371/JOURNAL.PGEN.0020150
Ling-Hui Li, Sheng-Feng Ho, Chien-Hsiun Chen, Chun-Yu Wei, Wan-Ching Wong, Li-Ying Li, Shuen-Iu Hung, Wen-Hung Chung, Wen-Han Pan, Ming-Ta M. Lee, Fuu-Jen Tsai, Ching-Fen Chang, Jer-Yuarn Wu, Yuan-Tsong Chen, Long contiguous stretches of homozygosity in the human genome Human Mutation. ,vol. 27, pp. 1115- 1121 ,(2006) , 10.1002/HUMU.20399
Mirjana Kujundžić-Tiljak, Zrinka Biloglav, Igor Rudan, Dinko Puntarić, Ariana Vorko-Jović, Darko Ropac, Harry Campbell, Branka Salzer, Branka Čučević, Ranko Stevanović, Effects of inbreeding, endogamy, genetic admixture, and outbreeding on human health: a (1001 Dalmatians) study. Croatian Medical Journal. ,vol. 47, pp. 601- 610 ,(2006)
Igor Rudan, Harry Campbell, Andrew D Carothers, Nicholas D Hastie, Alan F Wright, Contribution of consanguinuity to polygenic and multifactorial diseases Nature Genetics. ,vol. 38, pp. 1224- 1225 ,(2006) , 10.1038/NG1106-1224
Jane Gibson, Newton E. Morton, Andrew Collins, Extended tracts of homozygosity in outbred human populations Human Molecular Genetics. ,vol. 15, pp. 789- 795 ,(2006) , 10.1093/HMG/DDI493
Anne-Louise Leutenegger, Rehab Abdel-Rahman, Christopher S. Franklin, Marijana Pericic, Lovorka Barac-Lauc, Nina Smolej-Narancic, Branka Janicijevic, Ozren Polasek, Albert Tenesa, Andrew K. MacLeod, Susan M. Farrington, Pavao Rudan, Caroline Hayward, Veronique Vitart, Igor Rudan, Sarah H. Wild, Malcolm G. Dunlop, Alan F. Wright, Harry Campbell, James F. Wilson, Ruth McQuillan, Runs of Homozygosity in European Populations American Journal of Human Genetics. ,vol. 83, pp. 359- 372 ,(2008) , 10.1016/J.AJHG.2008.08.007
Igor Rudan, Diana Rudan, Harry Campbell, Andrew Carothers, Alan Wright, Nina Smolej-Narancic, Branka Janicijevic, Li Jin, Ranajit Chakraborty, Ranjan Deka, Pavao Rudan, Inbreeding and risk of late onset complex disease Journal of Medical Genetics. ,vol. 40, pp. 925- 932 ,(2003) , 10.1136/JMG.40.12.925