Uses of anti-cd40 antibodies
作者： Mohammad Luqman , Sharon Lea Aukerman
DOI:
关键词: Antibody 、 Genotype 、 Anti cd40 、 Rituximab 、 Refractory 、 CD20 、 CD40 、 Immunology 、 Autoimmune disease 、 Medicine
摘要: Methods for treating a human patient an inflammatory or autoimmune disease that is associated with CD40-expressing cells are provided, where the heterozygous homozygous FcϜRIIIa-158F (genotype V/F F/F). Also provided methods of inhibiting antibody production by B in who The comprise administering to therapeutically prophylactically effective amount anti-CD40 antibody. and kits identifying treatable which non-responsive refractory treatment rituximab (Rituxan®), as well selecting therapy having also provided. present invention find use diseases cells. These particularly advantageous respect expressing both CD40 CD20, enable patients other therapeutic agents such anti-CD20 antibodies.
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