Novel Promises of Nanotechnology for Tissue Regeneration

作者: Abir El-Sadik

DOI: 10.5772/25865

关键词: NanoparticleNanotechnologyNanoscopic scaleSurface-area-to-volume ratioApplications of nanotechnologyNanomaterialsMaterials scienceCeramicPolymerNanometre

摘要: The term ‘nanotechnology’ refers to technology that deals with structures and devices of nanometer (10 – 9 meter) size. It involves the design, fabrication utilization materials nanoscale dimensions (Gao & Xu, 2009). resulting nanomaterials exhibit chemical, physical biological properties can differ significantly from those bulk material. These products be categorized into metals, ceramics, polymers or composite have features. limited size their particles leads a high surface area volume ratio, improved solubility, multifunctionality, electrical heat conductivity catalytic activity. (El-Sadik et al., 2010). All these phenomena allow give nanoparticles interact systems at cellular molecular levels. interactions enhance biomedical applications nanotechnology giving great promise for improving disease prevention, diagnosis, treatment in particular tissue regeneration (Murthy, 2007).

参考文章(67)
Shashi K Murthy, Nanoparticles in modern medicine: state of the art and future challenges. International Journal of Nanomedicine. ,vol. 2, pp. 129- 141 ,(2007)
Bhranti S. Shah, Paul A. Clark, Eduardo K. Moioli, Michael A. Stroscio, Jeremy J. Mao, Labeling of mesenchymal stem cells by bioconjugated quantum dots Nano Letters. ,vol. 7, pp. 3071- 3079 ,(2007) , 10.1021/NL071547F
Matthew J. Dalby, Manus J.P. Biggs, Nikolaj Gadegaard, Gabriela Kalna, Chris D.W. Wilkinson, Adam S.G. Curtis, Nanotopographical stimulation of mechanotransduction and changes in interphase centromere positioning. Journal of Cellular Biochemistry. ,vol. 100, pp. 326- 338 ,(2007) , 10.1002/JCB.21058
Kyung Mi Woo, Ji-Hae Jun, Victor J. Chen, Jihye Seo, Jeong-Hwa Baek, Hyun-Mo Ryoo, Gwan-Shik Kim, Martha J. Somerman, Peter X. Ma, Nano-fibrous scaffolding promotes osteoblast differentiation and biomineralization. Biomaterials. ,vol. 28, pp. 335- 343 ,(2007) , 10.1016/J.BIOMATERIALS.2006.06.013
CY Xu, R Inai, M Kotaki, S Ramakrishna, Aligned biodegradable nanofibrous structure : a potential scaffold for blood vessel engineering Biomaterials. ,vol. 25, pp. 877- 886 ,(2004) , 10.1016/S0142-9612(03)00593-3
Jeff M. Bulte, Dara Kraitchman, Monitoring cell therapy using iron oxide MR contrast agents. Current Pharmaceutical Biotechnology. ,vol. 5, pp. 567- 584 ,(2004) , 10.2174/1389201043376526
Yan Hu, Kaiyong Cai, Zhong Luo, Rui Zhang, Li Yang, Linhong Deng, Klaus D. Jandt, Surface mediated in situ differentiation of mesenchymal stem cells on gene-functionalized titanium films fabricated by layer-by-layer technique. Biomaterials. ,vol. 30, pp. 3626- 3635 ,(2009) , 10.1016/J.BIOMATERIALS.2009.03.037
Michael Shin, Hiroshi Yoshimoto, Joseph P. Vacanti, In vivo bone tissue engineering using mesenchymal stem cells on a novel electrospun nanofibrous scaffold. Tissue Engineering. ,vol. 10, pp. 33- 41 ,(2004) , 10.1089/107632704322791673
Katsutoshi Kubo, Naoki Tsukimura, Fuminori Iwasa, Takeshi Ueno, Lei Saruwatari, Hideki Aita, Wen-An Chiou, Takahiro Ogawa, Cellular behavior on TiO2 nanonodular structures in a micro-to-nanoscale hierarchy model Biomaterials. ,vol. 30, pp. 5319- 5329 ,(2009) , 10.1016/J.BIOMATERIALS.2009.06.021
Gaëtan J-R Delcroix, Matthieu Jacquart, Laurent Lemaire, Laurence Sindji, Florence Franconi, Jean-Jacques Le Jeune, Claudia N Montero-Menei, None, Mesenchymal and neural stem cells labeled with HEDP-coated SPIO nanoparticles: in vitro characterization and migration potential in rat brain. Brain Research. ,vol. 1255, pp. 18- 31 ,(2009) , 10.1016/J.BRAINRES.2008.12.013