Pharmaco-metabonomic phenotyping and personalized drug treatment

作者: T. Andrew Clayton , John C. Lindon , Olivier Cloarec , Henrik Antti , Claude Charuel

DOI: 10.1038/NATURE04648

关键词: DrugAcetaminophenDiseasePharmacogenomicsMedicinePharmacogeneticsDistribution (pharmacology)BioinformaticsPharmacokineticsPharmacologyPharmacometabolomics

摘要: … Here we describe an alternative and conceptually new ‘pharmaco-metabonomic’ approach to personalizing drug treatment, which uses a combination of pre-dose metabolite profiling …

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