作者: T. Andrew Clayton , John C. Lindon , Olivier Cloarec , Henrik Antti , Claude Charuel
DOI: 10.1038/NATURE04648
关键词: Drug 、 Acetaminophen 、 Disease 、 Pharmacogenomics 、 Medicine 、 Pharmacogenetics 、 Distribution (pharmacology) 、 Bioinformatics 、 Pharmacokinetics 、 Pharmacology 、 Pharmacometabolomics
摘要: … Here we describe an alternative and conceptually new ‘pharmaco-metabonomic’ approach to personalizing drug treatment, which uses a combination of pre-dose metabolite profiling …