Effect of various synergists on toxicity and in vivo metabolism of DDT in Triatoma infestans nymphs
作者： B.C. Fine , María E. Letelier , M. Agosin
DOI: 10.1016/0014-4894(66)90080-4
关键词: Metabolism 、 In vivo metabolism 、 Toxicity 、 Dicofol 、 Nymph 、 Piperonyl butoxide 、 Triatoma infestans 、 Biology 、 Pesticide 、 Biochemistry 、 Toxicology
摘要: Abstract Piperonyl Butoxide, Sesoxane, WARF, and DMC were screened as synergists of DDT against Triatoma infestans nymphs. The most effective found to be the methylene dioxy phenyl compounds, which increased toxicity by a factor in excess 20. All inhibit oxidative detoxication 14C-DDT more polar metabolites. Curiously neither WARF nor inhibited conversation DDE. It is suggested that synergism will obtained when suitable inhibitors T. DDT-dehydrochlorinase are discovered.
cabdirect.org
elsevier.com
sci-hub.se 参考文章(10)
W. Klassen, J. B. Kitzmiller, W. J. Keppler, Toxicities of certain larvicides to resistant and susceptible Aedes aegypti (L.). Bulletin of The World Health Organization. ,vol. 33, pp. 117- 122 ,(1965)
Maria Luisa Dinamarca, Moises Agosin, Amador Neghme, The metabolic fate of C14-DDT in Triatoma infestans☆ Experimental Parasitology. ,vol. 12, pp. 61- 72 ,(1962) , 10.1016/0014-4894(62)90070-X
G. T. BROOKS, A. HARRISON, Structure-activity Relationships among Insecticidal Compounds derived from Chlordene Nature. ,vol. 205, pp. 1031- 1032 ,(1965) , 10.1038/2051031A0
A. MORELLO, ROLE OF DDT-HYDROXYLATION IN RESISTANCE. Nature. ,vol. 203, pp. 785- 786 ,(1964) , 10.1038/203785A0
A. S. Perry, W. M. Hoskins, Synergistic Action with DDT Toward Resistant House Flies1 Journal of Economic Entomology. ,vol. 44, pp. 839- 850 ,(1951) , 10.1093/JEE/44.6.839
A. S. Perry, W. M. Hoskins, Detoxification of DDT as a Factor in the Resistance of House Flies1 Journal of Economic Entomology. ,vol. 44, pp. 850- 857 ,(1951) , 10.1093/JEE/44.6.850
M. Agosin, N. Scaramelli, A. Neghme, Intermediary carbohydrate metabolism of Triatoma infestans (insecta; hemiptera)—I. Glycolytic and pentose phosphate pathway enzymes and the effect of DDT Comparative Biochemistry and Physiology. ,vol. 2, pp. 143- 159 ,(1961) , 10.1016/0010-406X(61)90145-1
M. Acosin, A. Morello, N. Scaramelli, Partial Characterization of the in Vivo Metabolites of DDT-C14 in Triatoma infestans1 Journal of Economic Entomology. ,vol. 57, pp. 974- 977 ,(1964) , 10.1093/JEE/57.6.974
T. Kimura, A. W. A. Brown, DDT-Dehydrochlorinase in Aedes aegypti Journal of Economic Entomology. ,vol. 57, pp. 710- 716 ,(1964) , 10.1093/JEE/57.5.710
F. J. Oppenoorth, DDT-resistance in the housefly dependent on different mechanisms and the action of synergists. Mededelingen van de Landbouwhogeschool en der Opzoekingsstations van de Staat te Gent. ,vol. 30, ,(1965)