作者: Krzysztof Śmietanka , Zenon Minta , Edyta Świętoń , Monika Olszewska , Michał Jóźwiak
DOI: 10.1080/03079457.2014.952221
关键词: Neuraminidase 、 Influenza A virus subtype H5N1 、 Virology 、 Flock 、 Veterinary medicine 、 Outbreak 、 Clade 、 Virus 、 Concomitant 、 Biology 、 Serology
摘要: In April/May 2013, four outbreaks of avian influenza virus (AIV) infections caused by H9N2 subtype were diagnosed in Poland fattening turkey flocks exhibiting a drop feed and water intake, depression, respiratory signs mortality. The subsequent serological survey carried out on samples collected between June 2012 September 2013 from 92 poultry detected positive sera two additional meat located the same province. analysis amino acids haemagglutinin neuraminidase glycoproteins revealed that viruses possessed molecular profiles suggestive low pathogenicity, avian-like SAα2,3 receptor specificity adaptation to domestic poultry. Phylogenetic studies showed these AIVs grouped within Eurasian clade wild bird-origin had no relationship with AIV circulating Middle East Far Asia over past decade. Experimentally infected SPF chickens index-case remained...