ChemInform Abstract: Asymmetric Iridium-Catalyzed Hydrogenation of 2-Methylindole Using Phosphite Ligands.
作者： Sergey E. Lyubimov , Dmitry V. Ozolin , Vadim A. Davankov
关键词: Iodine 、 2-Methylindole 、 Denticity 、 Asymmetric hydrogenation 、 Medicinal chemistry 、 Catalysis 、 Iridium 、 Ligand 、 Chemistry
摘要: The iridium-catalyzed asymmetric hydrogenation of 2-methylindole using monodentate phosphites and amidophosphites as ligands was examined. use iodine the additive resulted in increased enantioselectivity conversion 2-methylindole. Full up to 80% ee were obtained with a catalyst based on phosphite ligand.
sci-hub.se 参考文章(1)
Sergey E. Lyubimov, Dmitry V. Ozolin, Vadim A. Davankov, Asymmetric iridium-catalyzed hydrogenation of 2-methylindole using phosphite ligands Tetrahedron Letters. ,vol. 55, pp. 3613- 3614 ,(2014) , 10.1016/J.TETLET.2014.04.113