Design of protein crystals in the development of solid biomaterials

摘要: The design of protein crystals has become a growing field in materials science and biotechnology. Protein have immense potential for use as new porous that allow the precise arrangement exogenous compounds by metal coordination chemical conjugation solvent channels crystals. Generation novel crystal lattices regulation environments interfaces represent important efforts this field. In review, we focus on recent advances preparation 2D 3D several approaches including engineering, ligand-mediated assembly, interfacial coordination, symmetric assembly engineered proteins, genetic fusion domains, computational interfaces. A major advantage using solid is they can be utilized biomaterials accumulation functional molecules, such ions, complexes inorganic nanoparticles. used applications separation processes, heterogeneous enzymatic catalysis drug delivery systems. It expected engineering will provide remarkable science.