Methods of using a g protein-coupled receptor to identify peptide yy (pyy) secretagogues and compounds useful in the treatment of conditions modulated by pyy
作者： Zhi-Liang Chu , James N. Leonard , Robert M. Jones
DOI:
关键词: Endocrinology 、 Y2 receptor 、 Receptor 、 Chemistry 、 Peptide YY 、 GPR119 、 Internal medicine 、 Convulsive disorders 、 Stimulation 、 G protein-coupled receptor
摘要: The present invention relates to methods of using GPR119 receptor identify peptide YY (PYY) secretagogues and compounds useful in the treatment conditions modulated by PYY, such as stimulation NPY Y2 (Y2R). Agonists are therapeutic agents for treating or preventing a condition Y2R. Conditions PYY may be Y2R include bone-related conditions, metabolic disorders, angiogenesis-related ischemia-related convulsive malabsorptive cancers, inflammatory disorders.
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