Comorbidity of epilepsy and headache in patients with Sturge-Weber syndrome.

摘要: Sturge-Weber syndrome is associated with leptomeningeal angioma, trigeminal port-wine stain, epilepsy, and glaucoma. Clinically, many patients are observed to have both seizures headaches, but this has never been described in the literature. A questionnaire was mailed 190 reported comorbid epilepsy headache as identified by Foundation. Sixty-eight surveys were returned anonymously; 55 headaches. The median age at onset 8 years, a of three headaches per month. Fifty-eight percent felt that an equal or greater problem. Ibuprofen acetaminophen most frequently tried abortive medications; 22% had sumatriptan. Only neurologist suggesting use anticonvulsant preventive agent. Subjects family history earlier (7.5 vs 11 years; P = .02), those more likely report behavior problems (69% 33%; .02). reporting learning hemiparesis seizure onset. Migraine-like can be significant problem for syndrome. Despite this, triptans prophylactic medications (including anticonvulsants) used less than half patients. Correlations symptom suggest genetic substrate could one factor determining variable neurologic manifestations seen