Diagnostic performance of 18F‐fluorodeoxyglucose positron emission tomography in the evaluation of glioma

摘要: Introduction: Identifying glioma grade through imaging allows clinicians to recommend and accurately direct treatment. We sought quantify the utility of FDG-PET/CT (18F-fluorodeoxyglucose positron emission tomography/computed tomography), alone in combination with MRI, identifying high-grade regions glioma. Methods: This is a retrospective review patients who had an performed as part workup suspected or follow-up known scans were reviewed uptake identifiable lesion coded none, diffusely focally increased. Patients also underwent gadolinium-enhanced noting contrast enhancement. Sensitivity, specificity, positive negative predictive values (PPV NPV) calculated for identification histology (WHO III IV, metastatic disease) obtained post-FDG-PET/CT. Results: Thirty-three 36 MRI followed by histological confirmation (biopsy debulking). Increased FDG demonstrated sensitivity 59% specificity 79%, PPV 81% NPV 55% histology. 77% 86%, 89% 71% Only 64% scan series concordant. When concordant, 100% was achieved, however, 79% 75%. Conclusion: The marked improvement potential disease over each modality alone. without gadolinium enhancement rarely occurred identified small number patients. Due limited NPV, alone, should not guide decision observation where surgery would otherwise be recommended.