Fertility Treatment Options in Women Over 40 Years Old

作者: Michael G. R. Hull

DOI: 10.1007/978-1-4612-2288-0_23

关键词: Polycystic ovaryTotal fertility rateOvulation inductionObstetricsAge and female fertilityOvulationFertilityPregnancy rateMedicinePregnancy

摘要: The choice of fertility treatments in women over 40 years old must some cases be inferred from results achieved younger because specific information about is often lacking. Expectations can estimated knowledge the normal quantitative decline rates as age advances, and underlying mechanisms. first evidence clearly demonstrating true age-related inherent came donor insemination studies, which completely control for coital frequency spouse’s (Fig. 23.1) (1). Other early impact on treatment gonadotropin therapy to induce ovulation, by timing should optimized 23.2) (2). These studies demonstrate, first, that are inherently inefficient, therefore unsuited 40, who have no time waste. Figure 23.1 shows standard cervical using cryopreserved semen, now mandatory, offers at best—in young women—less than a 10% chance pregnancy each cycle, amounting 60% after 12 cycles. 23.2 demonstrates that, study (1980), ovulation with polycystic ovaries similarly inefficient. More refined regimens monitoring including ovarian ultrasonography recently been reported much improved success (PCO) (3), but related

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