Contamination of the nebulization systems used in the prophylaxis with amphotericin B nebulized in lung transplantation.

作者: V Monforte , A Román , J Gavalda , C Bravo , V Rodriguez

DOI: 10.1016/J.TRANSPROCEED.2005.09.189

关键词: Metered-dose inhalerSurgerySputum cultureAntibioticsTransplantationAnesthesiaAmphotericin BLung transplantationSputumNebulizerMedicine

摘要: The contamination of nebulizer may be the origin respiratory infections. aim this study was to determine incidence in nebulizers used nebulize amphotericin B lung transplant (LT) patients and relationship with bacterial isolation sputum culture. A prospective, cross-sectional conducted 41 LT who were administered a jet nebulizer. Samples taken from (prior nebulization). Sputum culture carried out asked whether or not they followed cleaning disinfection protocol (washing brushing soap water by subsequent Milton method after each Contamination defined as such when potentially pathogenic bacteria isolated Seventeen (41.4%) contaminated. In 7 17 cases (41.1%) polymicrobial. most common microorganism Pseudomonas aeruginosa. Fourteen (34.1%) presented positive cultures, P 10 (24.3%) both sputum. four these (9.7%) species same. 16 (39.0%). 2 (12.5%) following contaminated, compared 15 25 (60.0%) whose contaminated (P < .05). Two (12.%) 12 (48.0%) did conclusion, nebulizing systems is frequent no strict followed. Patients follow greater

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