Systemic effects of ionizing radiation at the proteome and metabolome levels in the blood of cancer patients treated with radiotherapy: the influence of inflammation and radiation toxicity.

作者: Karol Jelonek , Monika Pietrowska , Piotr Widlak

DOI: 10.1080/09553002.2017.1304590

关键词: ProteomeMetabolomeInflammationToxicityBiologyPathologyRadiation therapyIonizing radiationCancerMetabolomicsCancer research

摘要: AbstractPurpose: Blood is the most common replacement tissue used to study systemic responses of organisms different types pathological conditions and environmental insults. Local irradiation...

参考文章(95)
Neal L. Weintraub, W. Keith Jones, David Manka, Understanding radiation-induced vascular disease. Journal of the American College of Cardiology. ,vol. 55, pp. 1237- 1239 ,(2010) , 10.1016/J.JACC.2009.11.053
Elizabeth H. Donnelly, Jeffrey B. Nemhauser, James M. Smith, Ziad N. Kazzi, Eduardo B. Farfán, Arthur S. Chang, Syed F. Naeem, Acute radiation syndrome: assessment and management. Southern Medical Journal. ,vol. 103, pp. 541- 546 ,(2010) , 10.1097/SMJ.0B013E3181DDD571
Monika Pietrowska, Karol Jelonek, Joanna Polanska, Anna Wojakowska, Lukasz Marczak, Ewa Chawinska, Aleksanda Chmura, Wojciech Majewski, Leszek Miszczyk, Piotr Widlak, Partial-Body Irradiation in Patients with Prostate Cancer Treated with IMRT Has Little Effect on the Composition of Serum Proteome Proteome. ,vol. 3, pp. 117- 131 ,(2015) , 10.3390/PROTEOMES3030117
Sarah L. Kerns, Suman Kundu, Jung Hun Oh, Sandeep K. Singhal, Michelle Janelsins, Lois B. Travis, Joseph O. Deasy, A. Cecile J.E. Janssens, Harry Ostrer, Matthew Parliament, Nawaid Usmani, Barry S. Rosenstein, The Prediction of Radiotherapy Toxicity Using Single Nucleotide Polymorphism-Based Models: A Step Toward Prevention. Seminars in Radiation Oncology. ,vol. 25, pp. 281- 291 ,(2015) , 10.1016/J.SEMRADONC.2015.05.006
Ghazi Alsbeih, Michael D Story, Moshe H Maor, Fady B Geara, William A Brock, Chromosomal fragility syndrome and family history of radiosensitivity as indicators for radiotherapy dose modification. Radiotherapy and Oncology. ,vol. 66, pp. 341- 344 ,(2003) , 10.1016/S0167-8140(02)00327-4
Lisa M. Coussens, Zena Werb, Inflammation and cancer Nature. ,vol. 420, pp. 860- 867 ,(2002) , 10.1038/NATURE01322
Bradly G. Wouters, Proteomics: methodologies and applications in oncology Seminars in Radiation Oncology. ,vol. 18, pp. 115- 125 ,(2008) , 10.1016/J.SEMRADONC.2007.10.008
Xu-Wei Cai, Kerby A. Shedden, Shang-Hu Yuan, Mary A. Davis, Lu-Ying Xu, Cong-Ying Xie, Xiao-Long Fu, Theodore S. Lawrence, David M. Lubman, Feng-Ming (Spring) Kong, Baseline plasma proteomic analysis to identify biomarkers that predict radiation-induced lung toxicity in patients receiving radiation for non-small cell lung cancer. Journal of Thoracic Oncology. ,vol. 6, pp. 1073- 1078 ,(2011) , 10.1097/JTO.0B013E3182152BA6
Claudia E. Rübe, Jan Palm, Michael Erren, Jochen Fleckenstein, Jochem König, Klaus Remberger, Christian Rübe, Cytokine Plasma Levels: Reliable Predictors for Radiation Pneumonitis? PLoS ONE. ,vol. 3, pp. e2898- ,(2008) , 10.1371/JOURNAL.PONE.0002898
Monika Pietrowska, Joanna Polańska, Anna Walaszczyk, Andrzej Wygoda, Tomasz Rutkowski, Krzysztof Składowski, Łukasz Marczak, Maciej Stobiecki, Michał Marczyk, Andrzej Polański, Piotr Widłak, Association between plasma proteome profiles analysed by mass spectrometry, a lymphocyte-based DNA-break repair assay and radiotherapy-induced acute mucosal reaction in head and neck cancer patients. International Journal of Radiation Biology. ,vol. 87, pp. 711- 719 ,(2011) , 10.3109/09553002.2011.556174