Effect of l-ornithine hydrochloride ingestion on intermittent maximal anaerobic cycle ergometer performance and fatigue recovery after exercise

作者: Shinichi Demura , Koji Morishita , Takayoshi Yamada , Shunsuke Yamaji , Miho Komatsu

DOI: 10.1007/S00421-011-1896-1

关键词: OrnithineExercise physiologyCrossover studyIngestionInternal medicinePlaceboUrea cycleMedicineEndocrinologyAnaerobic exerciseUrea

摘要: L-Ornithine plays an important role in ammonia metabolism via the urea cycle. This study aimed to examine effect of L-ornithine hydrochloride ingestion on and performance after intermittent maximal anaerobic cycle ergometer exercise. Ten healthy young adults (age, 23.8 ± 3.9 year; height, 172.3 5.5 cm; body mass, 67.7 6.1 kg) with regular training experience ingested (0.1 g/kg, mass) or placebo 30 s cycling Five sets same exercise were conducted 60 min ingestion, was a 15 rest. The intensity based each subject's mass (0.74 N kg(-1)). Work volume (watt), peak rpm (rpm) before following serum parameters measured immediately exercise: ornithine, ammonia, urea, lactic acid glutamate. Peak significantly greater than ingestion. Serum ornithine level In conclusion, although may be improved by exercise, above not depend increase hydrochloride.

参考文章(29)
Oded Bar-Or, Omri Inbar, James S. Skinner, The Wingate Anaerobic Test ,(1996)
Charles D. Barnes, Donald G. Davies, Regulation of ventilation and gas exchange ,(1978)
Robert K. Murray..., Harper's Biochemistry ,(1998)
M N Goodman, J M Lowenstein, The purine nucleotide cycle. Studies of ammonia production by skeletal muscle in situ and in perfused preparations. Journal of Biological Chemistry. ,vol. 252, pp. 5054- 5060 ,(1977) , 10.1016/S0021-9258(17)40157-8
Juan J. ARAGON, John M. LOWENSTEIN, The Purine‐Nucleotide Cycle FEBS Journal. ,vol. 110, pp. 371- 377 ,(1980) , 10.1111/J.1432-1033.1980.TB04877.X
Marco Narici, Guido Ferretti, Davide Susta, Giovanni Faglia, Alessandro Sartorio, Maximum anaerobic performance of childhood-onset GH-deficient adults Growth Hormone & IGF Research. ,vol. 9, pp. 228- 235 ,(1999) , 10.1054/GHIR.1999.0112
B. Hindfelt, B.K. Siesjö, The effect of ammonia on the energy metabolism of the rat brain Life Sciences. ,vol. 9, pp. 1021- 1028 ,(1970) , 10.1016/0024-3205(70)90010-X
Seiichi Tsujino, Tomokazu Suzuki, Tsutomu Azuma, Sadayoshi Higa, Saburo Sakoda, Susumu Kishimoto, Hyperornithinemia, hyperammonemia and homocitrullinuria — a case report and study of ornithine metabolism using in vivo deuterium labelling Clinica Chimica Acta. ,vol. 201, pp. 129- 133 ,(1991) , 10.1016/0009-8981(91)90034-A