Integrating context of tumor biology and vaccine design to shape multidimensional immunotherapies

作者: Nathaniel S Wang , Christian J Maine

DOI: 10.4155/FDD-2019-0031

关键词: Cancer therapyTumor biologyContext (language use)MedicineBioinformatics

摘要: Advances in cancer therapy have offered great promise but only modest clinical benefits as monotherapies to date. Patients usually respond well therapies targeted at specific mutations, only...

参考文章(164)
F. M. Burnet, The concept of immunological surveillance. Progress in Experimental Tumor Research. ,vol. 13, pp. 1- 27 ,(1970) , 10.1159/000386035
Michael A. Postow, Manuarii Manuel, Phillip Wong, Jianda Yuan, Zhiwan Dong, Cailian Liu, Solène Perez, Isabelle Tanneau, Marlène Noel, Anaïs Courtier, Nicolas Pasqual, Jedd D. Wolchok, Peripheral T cell receptor diversity is associated with clinical outcomes following ipilimumab treatment in metastatic melanoma. Journal for ImmunoTherapy of Cancer. ,vol. 3, pp. 23- 23 ,(2015) , 10.1186/S40425-015-0070-4
Chunqing Guo, Masoud H. Manjili, John R. Subjeck, Devanand Sarkar, Paul B. Fisher, Xiang-Yang Wang, Therapeutic cancer vaccines: past, present, and future. Advances in Cancer Research. ,vol. 119, pp. 421- 475 ,(2011) , 10.1016/B978-0-12-407190-2.00007-1
Georg Widera, Melissa Austin, Dietmar Rabussay, Cheryl Goldbeck, Susan W. Barnett, Minchao Chen, Louisa Leung, Gillis R. Otten, Kent Thudium, Mark J. Selby, Jeffrey B. Ulmer, Increased DNA vaccine delivery and immunogenicity by electroporation in vivo. Journal of Immunology. ,vol. 164, pp. 4635- 4640 ,(2000) , 10.4049/JIMMUNOL.164.9.4635
Vijay Shankaran, Hiroaki Ikeda, Allen T. Bruce, J. Michael White, Paul E. Swanson, Lloyd J. Old, Robert D. Schreiber, IFNγ, and lymphocytes prevent primary tumour development and shape tumour immunogenicity Nature. ,vol. 410, pp. 1107- 1111 ,(2001) , 10.1038/35074122
Jay A. Berzofsky, Elizabeth A. Wiedenfeld, David P. Carbone, Marcelo Fernandez-Viña, Evidence for Selection against Human Lung Cancers Bearing p53 Missense Mutations Which Occur within the HLA A*0201 Peptide Consensus Motif Cancer Research. ,vol. 54, pp. 1175- 1177 ,(1994)
Gary E Grajales-Reyes, Arifumi Iwata, Jörn Albring, Xiaodi Wu, Roxane Tussiwand, Wumesh KC, Nicole M Kretzer, Carlos G Briseño, Vivek Durai, Prachi Bagadia, Malay Haldar, Jörg Schönheit, Frank Rosenbauer, Theresa L Murphy, Kenneth M Murphy, Batf3 maintains autoactivation of Irf8 for commitment of a CD8α(+) conventional DC clonogenic progenitor Nature Immunology. ,vol. 16, pp. 708- 717 ,(2015) , 10.1038/NI.3197
Ted P. Szatrowski, Carl F. Nathan, Production of Large Amounts of Hydrogen Peroxide by Human Tumor Cells Cancer Research. ,vol. 51, pp. 794- 798 ,(1991)
Joana Tato-Costa, Sandra Casimiro, Teresa Pacheco, Ricardo Pires, Afonso Fernandes, Irina Alho, Pedro Pereira, Paulo Costa, Henrique Bicha Castelo, João Ferreira, Luís Costa, None, Therapy-Induced Cellular Senescence Induces Epithelial-to-Mesenchymal Transition and Increases Invasiveness in Rectal Cancer Clinical Colorectal Cancer. ,vol. 15, pp. 170- 178 ,(2016) , 10.1016/J.CLCC.2015.09.003
Shabnam Shalapour, Michael Karin, Immunity, inflammation, and cancer: an eternal fight between good and evil Journal of Clinical Investigation. ,vol. 125, pp. 3347- 3355 ,(2015) , 10.1172/JCI80007