作者: John E. Cronan , Claire H. Birge , P. Roy Vagelos
DOI: 10.1128/JB.100.2.601-604.1969
关键词: Thioester 、 Enzyme 、 Unsaturated fatty acid 、 Biochemistry 、 Auxotrophy 、 Escherichia coli 、 Complementation 、 Biology 、 Cistron 、 Biosynthesis
摘要: Unsaturated fatty acid auxotrophs of Eschericha coli have been divided into two distinct cistrons by extract complementation and genetic based on abortive transduction. Lesions in one cistron result the loss beta-hydroxydecanoyl thioester dehydrase which produces first biosynthetic intermediate unsaturated formation. Evidence is presented indicates that lesions second lack a enzyme specifically involved biosynthesis acids.