Evidence for Two Genes Specifically Involved in Unsaturated Fatty Acid Biosynthesis in Escherichia coli

作者: John E. Cronan , Claire H. Birge , P. Roy Vagelos

DOI: 10.1128/JB.100.2.601-604.1969

关键词: ThioesterEnzymeUnsaturated fatty acidBiochemistryAuxotrophyEscherichia coliComplementationBiologyCistronBiosynthesis

摘要: Unsaturated fatty acid auxotrophs of Eschericha coli have been divided into two distinct cistrons by extract complementation and genetic based on abortive transduction. Lesions in one cistron result the loss beta-hydroxydecanoyl thioester dehydrase which produces first biosynthetic intermediate unsaturated formation. Evidence is presented indicates that lesions second lack a enzyme specifically involved biosynthesis acids.

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