Targeted Delivery Using Biodegradable Polymeric Nanoparticles

作者: Elias Fattal , Hervé Hillaireau , Simona Mura , Julien Nicolas , Nicolas Tsapis

DOI: 10.1007/978-1-4614-0881-9_10

关键词: Targeted nanoparticlesAllyl glycidyl etherPolymeric nanoparticlesPreparation methodNanoparticleChemistryTargeted drug deliveryNanotechnologyEthylene glycol

摘要: Biodegradable polymeric nanoparticles have been extensively used for targeted drug delivery mostly because of their potentialities to carry multifunctional properties. This chapter shows that can be made different types materials and prepared by multiple preparation methods allow the entrapment all drugs, small large, hydrophilic lipophilic. Moreover, this makes clear polymer chemistry discovery new grafting opened way modification, leading covalent linkage on surface either poly(ethylene glycol) long blood circulation time, or ligands specific biorecognition. The future such targeting systems relies targets will permit use in several therapeutic applications.

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