The risk of HIV and HCV infections among injection drug users in northeast India.
作者： Jagadish Mahanta , Biswajyoti Borkakoty , Hiranya Kumar Das , Pradeep Kumar Chelleng
DOI: 10.1080/09540120902862584
关键词: Viral hepatitis 、 Acquired immunodeficiency syndrome (AIDS) 、 Hepatitis B 、 Hepatitis 、 Hepatitis C 、 HBsAg 、 Risk factor 、 Virology 、 Medicine 、 Hepatitis B virus
摘要: Abstract Injection drug users (IDUs) and their associated risk behavior are responsible for driving the human immunodeficiency virus (HIV) epidemic in northeast India. So a group of IDUs from two northeastern states (Mizoram Nagaland) India were studied to find prevalence HIV, co-infection with hepatitis C (HCV), B (HBV), behaviors. Out 400 enrolled, 398 consented HCV, surface antigen (HbsAg) test. Of them, 10.8% HIV-1 antibody positive, 47.8% had HCV antibody, 3.8% detectable HBsAg. Among HIV infected subjects, 79.1% co-infected 6.9% triple infection. Heroin showed higher association (OR = 7.3, 95% CI: 2.5–21.5, p=0.0003) infection 7.6, 3.5–16.6, p<0.0001) than Spasmo-proxyvon (dextropropoxyphene, synthetic opiod analgesic). In summary, apart known variables among IDUs, type injecting drugs also influences HIV/HCV...
cabdirect.org
sci-hub.se 参考文章(10)
Kh Sulochana Devi, Ng Brajachand, Y Manihar Singh, H Lokhendro Singh, Co-infection by human immuno deficiency virus, hepatitis B and hepatitis C virus in injecting drug users. The Journal of communicable diseases. ,vol. 37, pp. 73- 77 ,(2005)
Yuan Li, Li Ye, Jin‐Song Peng, Chuan‐Qing Wang, Guang‐Xiang Luo, Ting Zhang, Qi Wan, Wen‐Zhe Ho, Morphine Inhibits Intrahepatic Interferon-α Expression and Enhances Complete Hepatitis C Virus Replication The Journal of Infectious Diseases. ,vol. 196, pp. 719- 730 ,(2007) , 10.1086/520093
Mark S. Sulkowski, David L. Thomas, Hepatitis C in the HIV-Infected Person Annals of Internal Medicine. ,vol. 138, pp. 197- 207 ,(2003) , 10.7326/0003-4819-138-3-200302040-00012
R. Detels, B. Manna, M. K. Saha, S. Panda, T. N. Naik, S. K. Bhattacharya, S. Chakrabarti, A. Chatterjee, Prevalence of HCV & HBV infection amongst HIV seropositive intravenous drug users & their non-injecting wives in Manipur, India. Indian Journal of Medical Research. ,vol. 111, pp. 37- 39 ,(2000)
Xu Wang, Ning Tan, Steven D. Douglas, Ting Zhang, Yan-Jian Wang, Wen-Zhe Ho, Morphine inhibits CD8+ T cell-mediated, noncytolytic, anti-HIV activity in latently infected immune cells. Journal of Leukocyte Biology. ,vol. 78, pp. 772- 776 ,(2005) , 10.1189/JLB.0305167
Stephen Koester, Jason Glanz, Anna Bar�n, Drug sharing among heroin networks: implications for HIV and hepatitis B and C prevention. Aids and Behavior. ,vol. 9, pp. 27- 39 ,(2005) , 10.1007/S10461-005-1679-Y
Padma Chandrasekaran, Gina Dallabetta, Virginia Loo, Sujata Rao, Helene Gayle, Ashok Alexander, Containing HIV/AIDS in India: the unfinished agenda Lancet Infectious Diseases. ,vol. 6, pp. 508- 521 ,(2006) , 10.1016/S1473-3099(06)70551-5
Vincent Soriano, Pablo Barreiro, Marina Nuñez, Management of chronic hepatitis B and C in HIV-coinfected patients Journal of Antimicrobial Chemotherapy. ,vol. 57, pp. 815- 818 ,(2006) , 10.1093/JAC/DKL068
Shyam Kottilil, Michael A. Polis, Julia O. Jackson, Hepatitis B & hepatitis C in HIV-infection. Indian Journal of Medical Research. ,vol. 121, pp. 424- ,(2005)
T. Stephen Jones, David Vlahov, Use of sterile syringes and aseptic drug preparation are important components of HIV prevention among injection drug users. Journal of Acquired Immune Deficiency Syndromes. ,vol. 18, ,(1998) , 10.1097/00042560-199802001-00002