Gas chromatography–mass spectrometry resolution of sugar acid enantiomers on a permethylated β-cyclodextrin stationary phase
作者： George Cooper , Minakshi Sant , Cynthia Asiyo
DOI: 10.1016/J.CHROMA.2009.07.073
关键词: Derivatization 、 Sugar acids 、 Gas chromatography 、 Cyclodextrin 、 Chromatography 、 Aldonic acid 、 Chemistry 、 Mass spectrometry 、 Organic chemistry 、 Isopropyl 、 Resolution (mass spectrometry) 、 Analytical chemistry 、 Biochemistry 、 General Medicine
摘要: Analysis of compounds in meteorites revealed a need to simultaneously characterize multiple enantiomers sugar acids (aldonic acids) present trace amounts. Analyses by gas chromatography-mass spectrometry demonstrated that all but two the three-carbon through six-carbon straight-chained acid enantiomer pairs could be resolved using single derivatization procedure and one set GC parameters. Compounds were analyzed as their ethyl ester/O-triflouroacetyl, isopropyl ester/O-triflouroacetyl ester/O-pentafluoropropionyl derivatives on capillary column containing permethylated beta-cyclodextrin (Chirasil-Dex CB) stationary phase. Characteristic mass fragments are related ester groups while several ions also common derivatized monosaccharides.
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