Phenolic compounds from the cultured mycobionts of Graphis proserpens

作者: Nobuo Hamada , Takao Tanahashi , Yukiko Takenaka , Natsuko Morimoto

DOI: 10.1016/J.PHYTOCHEM.2011.04.017

关键词: Organic chemistryIsocoumarinBenzoic acidChemistryStereochemistryGraphis proserpensSucrose

摘要: Spore-derived mycobionts of the lichen Graphis proserpens were cultivated on a malt-yeast extract medium supplemented with 10% sucrose and their metabolites investigated. Isocoumarin derivatives 1-3 7-oxo-5,7-dihydrooxepino[4,3,2-de]isochromene derivatives, proserins A-C (4-6), isolated along three known isocoumarin benzoic acid derivatives. Their structures determined by spectroscopic methods.

参考文章(9)
Ikuko Ohtani, Takenori Kusumi, Yoel Kashman, Hiroshi Kakisawa, High-field FT NMR application of Mosher's method. The absolute configurations of marine terpenoids Journal of the American Chemical Society. ,vol. 113, pp. 4092- 4096 ,(1991) , 10.1021/JA00011A006
Yukiko Takenaka, Takao Tanahashi, Naotaka Nagakura, Atsuko Itoh, Nobuo Hamada, Three isocoumarins and a benzofuran from the cultured lichen mycobionts of Pyrenula sp. Phytochemistry. ,vol. 65, pp. 3119- 3123 ,(2004) , 10.1016/J.PHYTOCHEM.2004.09.011
David P. Overy, John W. Blunt, Corymbiferan lactones from Penicillium hordei: stimulation of novel phenolic metabolites using plant tissue media. Journal of Natural Products. ,vol. 67, pp. 1850- 1853 ,(2004) , 10.1021/NP049723C
Takao Tanahashi, Yukiko Takenaka, Naotaka Nagakura, Nobuo Hamada, 6H-Dibenzo[b,d]pyran-6-one derivatives from the cultured lichen mycobionts of Graphis spp. and their biosynthetic origin Phytochemistry. ,vol. 62, pp. 71- 75 ,(2003) , 10.1016/S0031-9422(02)00402-8
Gemma Assante, Romano Locci, Lorenzo Camarda, Lucio Merlini, Gianluca Nasini, Screening of the genus Cercospora for secondary metabolites☆ Phytochemistry. ,vol. 16, pp. 243- 247 ,(1977) , 10.1016/S0031-9422(00)86794-1
Gerald W. McGraw, Richard W. Hemingway, 6-8-dihydroxy-3-hydroxymethyl-isocoumarin, and other phenolic metabolites of Ceratocystis minor Phytochemistry. ,vol. 16, pp. 1315- 1316 ,(1977) , 10.1016/S0031-9422(00)94393-0
Yukiko Takenaka, Nobuo Hamada, Takao Tanahashi, Structure and Biosynthesis of Lecanopyrone, a Naphtho(1,8-cd)pyran-3-one Derivative from Cultured Lichen Mycobionts of Lecanora leprosa Zeitschrift für Naturforschung C. ,vol. 65, pp. 637- 641 ,(2010) , 10.1515/ZNC-2010-11-1201
Takao Tanahashi, Yukiko Takenaka, Naotaka Nagakura, Nobuo Hamada, Naphthopyrones from cultured lichen mycobionts of Pyrenula sp. Heterocycles. ,vol. 81, pp. 1931- 1935 ,(2010) , 10.3987/COM-10-11989
Takeshi Kitahara, Kanako Uchida, Hidenori Watanabe, Takeo Usui, Hiroyuki Osada, SYNTHESES AND BIOACTIVITIES OF ACETOPHTHALIDIN AND ITS DERIVATIVES Heterocycles. ,vol. 48, pp. 2049- 2060 ,(1998) , 10.3987/COM-98-8246