Click Modification of Diazido Acridine Intercalators: A Versatile Route towards Decorated DNA Nanostructures

作者: Shahrbanou Moradpour Hafshejani , Scott M. D. Watson , Eimer M. Tuite , Andrew R. Pike

DOI: 10.1002/CHEM.201501836

关键词: Intercalation (chemistry)FluorescenceProflavineAcridineClick chemistryPolymer chemistryDNACombinatorial chemistryChemistrySurface modificationNanomaterials

摘要: Diazido derivatives of 3,6-diamino acridine (proflavine) intercalate into DNA and undergo functionalization through click chemistry to form 1D nanostructures with redox active, conductive nanowire, fluorescent properties. This two-step approach, intercalation followed by modification allows for the controlled decoration nanostructures.

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