Serum lipid response to a fat-modified, oatmeal-enhanced diet.

摘要: Abstract The purpose of this study was to confirm and extend previous findings that serum cholesterol response a fat-modified diet is enhanced by oat fiber. Participants ( n = 236) were recruited from the Continental Illinois National Bank in Chicago. Data including weight, lipid level, lipoproteins, 3-day food records collected at baseline every 4 weeks for 12 weeks. All participants instructed follow (Phase II) recommended American Heart Association (AHA). After weeks, randomly assigned one two groups. While both groups continued AHA diet, Group 1 include 2 oz (56 g, dry wt) oatmeal, isocalorically substituted other carbohydrate foods. served as control consumed no products throughout study. Serum values after similar (203.9 193.0 mg/dl 205.3 194.5 2). oatmeal intervention, mean group differences −6.8 −2.1 P 0.008 one-tailed t test) Groups 2, respectively. Following an additional increased slightly (0.9 mg/dl), while level decreased (−0.7 mg/dl). Overall responses Visit −6.0 −2.8 respectively 0.074, tail). Changes weight small nonsignificant. Subgroup analyses revealed greater reductions among with highest (−8.0 vs −1.7 Subgroups respectively). These data support inclusion helpful lowering cholesterol, particularly individuals elevated levels.