Compositions for treating glaucoma containing a carbostyril

作者: Nobuyuki Tanaka , Kazuyuki Nakagawa , Yoichi Nishinakamura

DOI:

关键词: Medicinal chemistryAlkoxy groupDouble bondStereochemistryChemistrySingle bondSubstituentGlaucomaAlkyl

摘要: This invention provides a glaucoma treating composition comprising at least one of carbostyril derivatives represented by the formula ##STR1## wherein R1 is hydrogen, lower alkyl or alkenyl, R2 hydrogen group ##STR2## R4 alkyl, cycloalkyl, substituted phenyl with without alkoxy substituent on nucleus, R3 ##STR3## as defined above when hydroxyl, ureido, alkynyloxy, having alkanoyl substitutent, alkanoylamino alkenyloxy ##STR4## and carbon-to-carbon bond between 3-position 4-position skeleton single double bond, pharmacologically acceptable acid addition salts thereof; method administering said to patient glaucoma.

参考文章(8)
Shiro Yoshizaki, Kazuyuki Nakagawa, Hideo Mori, Nanami Murakami, Carbostyril derivatives and process for preparing the same ,(1973)
Yoichi Yabuuchi, Kazuyuki Nakagawa, Shiro Yoshizaki, Medicament against glaucoma ,(1980)
Shiro Yoshizaki, Shigeharu Tamada, Kazuyuki Nakagawa, Kaoru Tanimura, 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-hydroxy-3,4-dihydrocarbostyril derivatives ,(1974)
Shiro Yoshizaki, Shigeharu Tamada, Kazuyuki Nakagawa, Kaoru Tanimura, 5-[1-Hydroxy-2-(substituted-amino)]ethyl-8-hydroxy-3,4-dihydrocarbostyril derivatives ,(1974)
Nishi Takao, Nakagawa Kazuyuki, Ueda Takashi, 3*44DIHYDROCARBOSTYRIL DERIVATIVE ,(1979)