The structural and functional heterogeneity of glutamic acid decarboxylase: a review.

作者: Mark G. Erlander , Allan J. Tobin

DOI: 10.1007/BF00966084

关键词: Glutamate decarboxylasePyridoxal phosphateBiologyBiochemistrygamma-Aminobutyric acidEnzymeComplementary DNAGene

摘要: Studies of the GABA-synthetic enzyme glutamate decarboxylase (glutamic acid decarboxylase; GAD; EC4.1.1.15) began in 1951 with the work of Roberts and his colleagues. Since then…

参考文章(106)
J. Dudel, R. Gryder, A. Kaji, S. W. Kuffler, D. D. Potter, GAMMA-AMINOBUTYRIC ACID AND OTHER BLOCKING COMPOUNDS IN CRUSTACEA: I. CENTRAL NERVOUS SYSTEM Journal of Neurophysiology. ,vol. 26, pp. 721- 728 ,(1963) , 10.1152/JN.1963.26.5.721
Samuel P. Bessman, Jack Rossen, Ennis C. Layne, γ-AMINOBUTYRIC ACID-GLUTAMIC ACID TRANSAMINATION IN BRAIN Journal of Biological Chemistry. ,vol. 201, pp. 385- 391 ,(1953) , 10.1016/S0021-9258(18)71381-1
Eugene. Roberts, Sam. Frankel, Further studies of glutamic acid decarboxylase in brain. Journal of Biological Chemistry. ,vol. 190, pp. 505- 512 ,(1951) , 10.1016/S0021-9258(18)55998-6
D C Spink, T G Porter, S J Wu, D L Martin, Characterization of three kinetically distinct forms of glutamate decarboxylase from pig brain Biochemical Journal. ,vol. 231, pp. 695- 703 ,(1985) , 10.1042/BJ2310695
Eugene Roberts, Fred Younger, Sam Frankel, Influence of dietary pyridoxine on glutamic decarboxylase activity of brain. Journal of Biological Chemistry. ,vol. 191, pp. 277- 285 ,(1951) , 10.1016/S0021-9258(18)50976-5
T G Porter, D C Spink, S B Martin, D L Martin, Transaminations catalysed by brain glutamate decarboxylase Biochemical Journal. ,vol. 231, pp. 705- 712 ,(1985) , 10.1042/BJ2310705
Jorge Awapara, Alton J. Landua, Robert Fuerst, Billie Seale, FREE γ-AMINOBUTYRIC ACID IN BRAIN Journal of Biological Chemistry. ,vol. 187, pp. 35- 39 ,(1950) , 10.1016/S0021-9258(19)50926-7
T L Doering, W J Masterson, G W Hart, P T Englund, Biosynthesis of glycosyl phosphatidylinositol membrane anchors. Journal of Biological Chemistry. ,vol. 265, pp. 611- 614 ,(1990) , 10.1016/S0021-9258(19)40092-6
Eugene. Roberts, Sam. Frankel, Glutamic acid decarboxylase in brain. Journal of Biological Chemistry. ,vol. 188, pp. 789- 795 ,(1951) , 10.1016/S0021-9258(19)77753-9