Transgenic animal expressing non-native wild-type and familial alzheimer's disease mutant presenilin 1 protein on native presenilin 1 null background
作者： Sangram S. Sisodia , Su Qian , Leonardus H. T. Van Der Ploeg , Hui Zheng , Philip Chun-Ying Wong
DOI:
关键词: Central nervous system 、 Presenilin 、 Familial Alzheimer's disease 、 Mutant 、 Genetics 、 Biology 、 Expression pattern 、 Embryo 、 Wild type 、 Transgene
摘要: The present invention relates to a transgenic non-human animal embryo lacking native presenilin 1 and having only non-native 1. animals cells derived therefrom can be used in the study of expression pattern, activity modulators 1, role Alzheimer's Disease disorders central nervous system.
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