Di- and triazidation of 3-chlorotetrafluoropyridine
作者： Sergei V. Chapyshev
DOI: 10.1016/J.JFLUCHEM.2011.07.012
关键词: Reaction conditions 、 Reagent 、 Sodium azide 、 Cross-Linking Reagents 、 Organic synthesis 、 Nucleophilic substitution 、 Organic chemistry 、 Chemistry 、 Regioselectivity 、 Physical and Theoretical Chemistry 、 Inorganic chemistry 、 Biochemistry 、 Environmental chemistry
摘要: Abstract 3-Chlorotetrafluoropyridine and pentafluoropyridine readily react with an excess of sodium azide in dimethylsulfoxide at room temperature to give corresponding 2,4,6-triazido-3-chloro-5-fluoropyridine 2,4,6-triazido-3,5-difluoropyridine high yields. The reaction asymmetric 3-chlorotetrafluoropyridine two equimolar amounts under similar conditions occurs regioselectively 2,4-diazido-5-chloro-3,6-difluoropyridine as a sole product. 19 F, 13 C 15 N NMR spectral characteristics the triazides suggest that these compounds can be interest cross-linking reagents for polymer chemistry starting materials organic synthesis.
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