Low frequency amplitude modulated microwave fields change calcium efflux rates from synaptosomes.
作者： S. Lin-Liu , W. R. Adey
关键词: Efflux 、 Biophysics 、 Microwave 、 Calcium 、 Calcium Compounds 、 Low frequency 、 Amplitude modulation 、 Chemistry 、 Isotopes of calcium 、 Calcium in biology
摘要: Calcium (45Ca2+) efflux from preloaded synaptosomes was studied with a continuous perfusion technique and the rate constants of two-phase process calculated. When 16-Hz sinusoidally amplitude modulated 450-MHz microwave field (maximal incident intensity 0.5 mW/cm2, modulation depth 75%) applied during second phase, constant increased by 38%. Unmodulated or 60-Hz signals were not effective. This field-induced change can be distinguished CaCl2-stimulated 45Ca2+ which is most probably derived intracellularly. These data suggest that microwave-field induced in calcium did involve intracellular calcium. Also, this dynamic property require gross anatomically intact tissue as substrate for field-tissue interaction.
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