Relationship of menstrual cycle and vaginal infection in female rhesus macaques challenged with repeated, low doses of SIVmac251.

作者: Monica R. Morris , Siddappa N. Byrareddy , Francois Villinger , Tara C. Henning , Katherine Butler

DOI: 10.1111/JMP.12177

关键词: VaginaSimian immunodeficiency virusVaginal infectionsMenstruationRhesus macaqueMenstrual cyclePhysiologyMedicineHiv transmissionLow doseImmunology

摘要: Varying susceptibility during menstrual cycling could be a factor for S(H)IV infection risk in female rhesus macaques. We retrospectively determined vaginal SIV time points relative to the cycle group of macaques (n=11) enrolled an HIV transmission trial. Eight nine became infected around menstruation time.

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