Use of healthcare resources among medically and surgically treated patients with gastroesophageal reflux disease: a population-based study.

作者: Michael D Holzman , Edward F Mitchel , Wayne A Ray , Walter E Smalley

DOI: 10.1016/S1072-7515(00)00746-8

关键词: Medical prescriptionSurgeryHealth careCohortDiseaseMedicineInternal medicineEsophageal diseaseMedicaidRefluxGERD

摘要: Abstract Background: Gastroesophageal reflux disease (GERD) is a common disorder that may be effectively managed medically or surgically. Direct evaluations of medical resource use are needed to better understand the relative costs these alternatives. This study compared care for group patients receiving surgical treatment GERD with comparable management. Study Design: We conducted retrospective matched cohort Tennessee Medicaid (TennCare) undergoing in 1996 and who received therapy during same period. Administrative TennCare data provided computerized records could used identify measure healthcare use. There were 7,502 people met all conditions inclusion study, including at least two encounters diagnosis GERD. One hundred thirty-five underwent fundoplication constituted surgically treated cohort. The 250 persons selected randomly from remaining nonsurgical by age, gender, race, organization, acid suppression drug baseline year. principal outcome interest was total resources, prescription medication. Results: cohorts did not differ significantly demographic characteristics pharmaceuticals. During year prescribed 302 (95% CI: 270–334) days 292 267–317) treatment. Surgically more GERD-related outpatient resources (physician visits diagnostic testing) year, particularly 3 months before operation, when they had mean than four encounter-days. In followup pharmaceuticals decreased markedly These an average 123 94–153) therapy, which only 36% (339 [95% 308–370]). More 29% no drugs 6% group. number inpatient procedure 3.2 2.7–3.6), range 0 13 days. differences between groups other Conclusions: Our results show 1-year period followup, severe gastroesophageal led 64% postsurgical reduction medication use, increase services.

参考文章(31)
David J. Hetzel, John Dent, William D. Reed, Firoze M. Narielvala, M. Mackinnon, Justin H. McCarthy, Brent Mitchell, Bruce R. Beveridge, Bernard H. Laurence, Geoffrey G. Gibson, Alan Kerr Grant, David J.C. Shearman, Richard Whitehead, Peter J. Buckle, Healing and relapse of severe peptic esophagitis after treatment with omeprazole Gastroenterology. ,vol. 95, pp. 903- 912 ,(1988) , 10.1016/0016-5085(88)90162-X
K.-H. Fuchs, H. Feussner, L. Bonavina, J. M. Collard, W. Coosemans, Current status and trends in laparoscopic antireflux surgery: Results of a consensus meeting Endoscopy. ,vol. 29, pp. 298- 308 ,(1997) , 10.1055/S-2007-1004194
N I McDougall, B T Johnston, F Kee, J S Collins, R J McFarland, A H Love, Natural history of reflux oesophagitis: a 10 year follow up of its effect on patient symptomatology and quality of life. Gut. ,vol. 38, pp. 481- 486 ,(1996) , 10.1136/GUT.38.4.481
Jouko Isolauri, Markku Luostarinen, Mikko Viljakka, Erika Isolauri, Olavi Keyriläinen, Anna-Liisa Karvonen, Long-term comparison of antireflux surgery versus conservative therapy for reflux esophagitis. Annals of Surgery. ,vol. 225, pp. 295- 299 ,(1997) , 10.1097/00000658-199703000-00009
K. Huibregtse, J. Cheng, E. A. J. Rauws, G. N. J. Tytgat, Postoperative Biliary Strictures: The Endoscopic Approach Scandinavian Journal of Gastroenterology. ,vol. 24, pp. 50- 56 ,(1989) , 10.3109/00365528909091373
David S. Weinberg, Steven L. Kadish, The diagnosis and management of gastroesophageal reflux disease Medical Clinics of North America. ,vol. 80, pp. 411- 429 ,(1996) , 10.1016/S0025-7125(05)70446-6
Theodore R Levin, Julie A Schmittdiel, Kimberly Kunz, James M Henning, Curtis J Henke, Chris J Colby, Joseph V Selby, Costs of Acid-related Disorders to a Health Maintenance Organization The American Journal of Medicine. ,vol. 103, pp. 520- 528 ,(1997) , 10.1016/S0002-9343(97)00308-2
P. A. Van Liessum, P. H. M. De Mulder, L. D. De Haan, Nausea and Vomiting Induced by Cytostatic Agents Scandinavian Journal of Gastroenterology. ,vol. 24, pp. 106- 111 ,(1989) , 10.3109/00365528909091380
Otto T. Nebel, Michael F. Fornes, Donald O. Castell, Symptomatic gastroesophageal reflux: Incidence and precipitating factors The American Journal of Digestive Diseases. ,vol. 21, pp. 953- 956 ,(1976) , 10.1007/BF01071906
L. Sölvell, The Clinical Safety of Omeprazole Scandinavian Journal of Gastroenterology. ,vol. 166, pp. 106- 110 ,(1989) , 10.3109/00365528909091255