作者: Bruce W. Lytle , Delos M. Cosgrove , Paul C. Taylor , Marlene Goormastic , Robert W. Stewart
DOI: 10.1016/S0022-5223(19)34513-1
关键词: Internal medicine 、 Aortic valve replacement 、 Uremia 、 Late results 、 Aortic valve 、 Coronary artery disease 、 Atrial fibrillation 、 Medicine 、 Risk factor 、 Cardiology 、 Blood urea nitrogen
摘要: A total of 1689 consecutive patients underwent isolated aortic valve replacement at the Cleveland Clinic Foundation from 1972 through 1986. There were 57 (3.4%) in-hospital deaths. Multivariate analysis identified advanced age (p = 0.0014), preoperative blood urea nitrogen level greater than 25 mg/100 ml 0.008), New York Heart Association function class 0.015), and atrial fibrillation 0.04) as independent variables associated with increased mortality use cardioplegia for myocardial protection 0.006) a factor decreasing mortality. Follow-up documented survival rates 85% 66% event-free 71% 43% 5 10 postoperative years, respectively. Advanced age, moderate or severe impairment left ventricular function, coronary artery disease, decreased late (all p